Operations Engineer at Pfizer

Pfizer Singapore is recruiting permanent employees for manufacturing site expansion of PFIZER ASIA MANUFACTURING PTE LTD (PAMPL) in Singapore.

Why Patients Need You:

Our breakthroughs would not make it to the hands of patients without our pharmaceutical manufacturing team. We rely on a team of dedicated and agile members, who understand the importance and impact of their role in Pfizer’s mission. Patients need colleagues like you who take pride in their work and always look to improve outcomes. You will help to ensure that patients and physicians have the medicines they need, when they need them.

What You Will Achieve:

Your expertise in the manufacturing domain will help in analyzing and designing a sequence of operations and workflow to improve the company's production facilities within regulations and Good Manufacturing Practices. You will be involved in activities, such as process monitoring, safety and environmental improvements, process reliability improvements, validation, and technology transfers. You will also conduct studies pertaining to cost control and reduction, inventory control, and production record systems. On the basis of these studies, you will develop and implement plans and programs for facility modifications and revisions to operating methods.

As an associate, your focus on the job will contribute in achieving project tasks and goals. Through your domain knowledge and commitment, you will create a collaborative teaming environment for your colleagues.

It is your hard work and focus that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It:

Support plant operations in the end to end manufacture (inclusive of changeover) of Active Pharmaceutical Ingredients (APIs) in compliance with Good Manufacturing Practices (GMP) and Standard Operating Procedures (SOPs).

Collaborate cross-functionally to ensure safety, quality, and operational investigations are thoroughly conducted and reported in a timely manner.

Contribute to continuous improvement initiatives, including IMEX activities and the development, implementation, and periodic review of documentation that enhances operational effectiveness and regulatory compliance.

Support all aspects of manufacturing operations while ensuring full compliance with environmental, health, and safety (EHS) regulations

Maintain a state of perpetual safety and GMP compliance on the shop floor, ensuring audit-readiness at all times

Execute production, pre-maintenance, and post-maintenance intervention activities to meet manufacturing targets and reduce equipment downtime

Ensure that pre-manufacturing checks are performed safely, compliantly in order to meet manufacturing plan

Review operational tasks in alignment with Manufacturing Standard Work (MSW) and Operation Standard Work (OSW) to optimize workflow efficiency

Participate in troubleshooting activities for processing issues and deviations, collaborating cross-functionally to drive immediate and preventive actions to meet manufacturing targets and reduce equipment downtime

Contribute to EHS and quality investigations, generate reports, and drive resolution of issues identified during operations, batch record review, cleaning instructions review and associated manufacturing documentation

Drive Continuous Improvement (CI) initiatives using the Plan-Do-Check-Act (PDCA) methodology to enhance safety, quality, and productivity

Support the development of risk assessments and job safety assessments (JSAs); participate in HAZOP reviews as needed

Author and review Standard Operating Procedures (SOPs); ensure SOPs remain current and compliant

Assist in commissioning, qualification, and validation (CQV) activities to support new equipment and process readiness

Participate as a member of the emergency response team (ERT) when necessary.

Development and review of changeover cleaning documentation and maintaining cleaning validation status

Development of changeover cleaning schedule and communication with cross functional departments for timely release of equipment for production

Support manufacturing campaigns and changeover cleaning on rotating shift basis, as required

Provide technical guidance for management of alarm responses and ensure alarm response is timely, appropriate and assessed as per SOP. Ensure that interlock bypass is performed safely and compliantly as per SOP

Conduct hands on training including Structured On the Job Training (SOJT), Instructor Led Training (ILT), Job Safety Analysis (JSA), SOPs

Perform structured gemba on operational activities for continuous improvement opportunities and active participation in good save initiative

Accountable for:

Safe operation of plant and equipment

Safety, cGMP, GDP, and SOP compliance

Ensuring delivery of production plan inclusive of manufacturing and changeover cleaning

Qualifications:

Must-Have

Degree in Engineering, preferably in Chemical Engineering

Demonstrated ability to lead people or processes

Laboratory experience required (testing, data reviewing, or other supporting activities for laboratory operation)

Basic functional and technical knowledge of the discipline

Good organization skills and attention to detail

Ability to document clearly and concisely

Effective written and oral communication

Knowledge of Microsoft Application:

Core Competencies:

Technical Knowledge, Communication, Teamwork, Leadership, Project Management, Curiosity & Innovation, Self-motivated and independent

Nice-to-Have

Preferably, 2-3 years’ experience in a relevant manufacturing environment in Pharmaceutical / Chemical / Petrochemical industry.

Indirect leadership experience {e.g. testing/team Subject Matter Expert project lead, training lead)

Demonstrate proficiency in computerized systems, experience and use of Laboratory Information Management System and Quality Tracking System

Work Location Assignment: On Premise

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

Manufacturing