Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

GRAIL is seeking a Director, Software Product Management, Commercial Software to lead the strategy, roadmap, and execution of our commercial software portfolio. This leader will play a critical role in shaping the systems that power our commercial operations and enable healthcare providers, patients, and partners to access and adopt our life-saving technologies. You will join a cross-functional organization spanning engineering, commercial, laboratory operations, billing, legal, quality, and finance to deliver scalable, secure, and compliant software solutions in a highly regulated clinical environment.

This role requires both strategic vision and operational rigor — someone who can define long-term product direction while driving disciplined execution, balancing customer experience, commercial outcomes, and regulatory requirements.

This role is based in Menlo Park, California, and will move to Sunnyvale, California in Fall 2026. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 40% requirement for the site. At our Menlo Park campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities.