
Multinational biopharmaceutical company.
Principal Systems Engineer – Clinical Computation Platform at Amgen
About the role
Career Category
Clinical
Job Description
ABOUT AMGEN
Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer. We discover, develop, manufacture and deliver innovative medicines to help millions of patients. Amgen helped establish the biotechnology industry more than 40 years ago and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what’s known today.
ABOUT THE ROLE:
Role Description:
The role is responsible for the design, integration, and management of complex systems that encompass both hardware and software components into the organization’s cloud infrastructure. This individual will be responsible for all activities related to handling and supporting the Business and platforms including system administration, as well as incorporating new technologies under the challenge of a sophisticated and constantly evolving technology landscape. This role involves ensuring that all parts of a system work together seamlessly to meet the organization’s requirements.
Roles & Responsibilities:
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Collaborate with business partners and other software engineers to develop and deploy the latest, advanced technologies in support of product optimization
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Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines
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Support selected efforts to design, build, and develop rapid Proof-of-Concept (POC) automated solutions and services. Quickly and iteratively prove or disprove the concepts being considered
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Develop and design systems architecture, ensuring that it meets both current and future needs of the organization
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Integrate hardware and software components into a cohesive system that meets functional and performance requirements
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Perform system testing and validation to ensure all components function correctly and efficiently
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Optimize system performance and troubleshoot any issues that arise during system operation
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Create and maintain comprehensive documentation of systems design, configurations, and procedures
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Work closely with other engineers, IT staff, and project managers to ensure successful implementation of systems
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Monitor and maintain systems to ensure they continue to operate effectively and efficiently
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Implement automation tools and processes to improve the efficiency and reliability of the system
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Conduct training and workshops for business teams to share best practices in the industry.
Basic Qualifications and Experience:
- Master’s / Bachelor’s degree with 13 - 17 years of experience in Computer Science, IT or related field
Functional Skills:
Must-Have Skills:
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Experience in cloud platforms including AWS
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Experience with container technologies like Docker and Kubernetes
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Hands-on experience with computerized systems including troubleshooting, reliability, and performance improvements
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Experience with translating business requirements to technical requirements and recommend solutions for automation
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Proficiency in programming languages including R, Python
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Experience and strong knowledge of POSIT Tools and Services
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Strong understanding of software development methodologies, including Agile and Scrum
Good-to-Have Skills:
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Experience with DevOps tools and practices
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Strong understanding of systems engineering processes and methodologies
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Experience with systems integration and validation
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Knowledge of Clinical Development domain
Professional Certifications:
- Scaled Agile Framework (SAFe) for Teams (preferred)
Soft Skills:
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Excellent analytical and troubleshooting skills
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Strong verbal and written communication skills
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Ability to work effectively with global, virtual teams
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High degree of initiative and self-motivation
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Ability to manage multiple priorities successfully
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Team-oriented, with a focus on achieving team goals
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Strong presentation and public speaking skills
Shift Information:
This position requires you to work a later shift and may be assigned a second or third shift schedule. Candidates must be willing and able to work during evening or night shifts, as required based on business requirements.
EQUAL OPPORTUNITY STATEMENT:
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
.
Required skills
Systems engineering
Cloud infrastructure
Platform support
Automation
System integration
Architecture
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About Amgen

Amgen
PublicA biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10,001+
Employees
Thousand Oaks
Headquarters
$138B
Valuation
Reviews
24 reviews
3.6
24 reviews
Work-life balance
3.2
Compensation
3.5
Culture
3.1
Career
2.8
Management
3.4
65%
Recommend to a friend
Pros
Excellent benefits and health benefits
Good pay and compensation
Supportive management and leadership
Cons
Limited career growth and promotion opportunities
Work-life balance challenges and long hours
Bureaucratic processes
Salary Ranges
1,002 data points
L2
L6
L3
L4
L5
L2 · Financial Analyst L2
0 reports
$94,068
total per year
Base
$37,627
Stock
$47,034
Bonus
$9,407
$65,848
$122,288
Interview experience
5 interviews
Difficulty
3.0
/ 5
Duration
14-28 weeks
Offer rate
40%
Experience
Positive 20%
Neutral 80%
Negative 0%
Interview process
1
Application Review
2
Recruiter Screen
3
Hiring Manager Interview
4
Technical/Case Interview
5
Final Round/Panel Interview
6
Offer
Common questions
Technical Knowledge
Behavioral/STAR
Past Experience
Case Study
Culture Fit
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