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Bioinformatics Scientist, Assay Design and Pipelines

Thermo Fisher

Bioinformatics Scientist, Assay Design and Pipelines

Thermo Fisher

Singapore, Singapore

·

On-site

·

Full-time

·

2w ago

Required Skills

Python

Bioinformatics

Genomics

Molecular biology

Data analysis

Problem-solving

Communication

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description Position Summary

We are seeking a skilled and motivated Bioinformatics Scientist to join our team, specializing in assay and content development for qPCR, dPCR, and CE technologies. The role focuses on delivering high-quality assays on schedule and contributing to the development and maintenance of computational pipelines, databases, and infrastructure to scale assay development. This position requires strong domain knowledge of genomics, PCR-based methods, and proficiency in bioinformatics pipeline development. You will convert biological questions into assay strategies and assign robust primer/probe sets. You will streamline workflows and optimize code for efficiency and scalability. Collaboration with other bioinformatics scientists, product management, and customer support colleagues is essential.

Primary Responsibilities

  • Design, develop, and optimize qPCR assays for various applications, including gene expression, genotyping, copy number analysis, and pathogen detection.
  • Analyze and interpret complex genomic and sequence data to support target selection and assay development.
  • Develop, maintain, and optimize bioinformatics pipelines and workflow automation for large-scale assay development.
  • Maintain version-controlled repositories, documentation, and reproducibility across computational workflows.
  • Participate in the publication or productization of developed algorithms, pipelines, or tools
  • Prepare and present scientific reports and presentations to communicate findings and progress.

Required Qualifications

  • Degree or Masters degree in bioinformatics, Computational Biology, Molecular Biology, Bioinformatics, or related fields. Preferred with 2 years of relevant experience.
  • Strong genomics & molecular biology domain knowledge in at least one of the domains in plants, mammalian, microbial, and oncology systems.
  • Bioinformatics stack: IGV, BLAST, BWA/other aligners; major databases (Gen Bank, Ensembl); experience across genomics, and quantitative data with strong analytical, problem-solving skills.
  • Strong programming for scripting: Advanced Python
  • Teaming & execution: excellent communication; effective cross-functional collaboration; able to work independently and manage multiple projects concurrently.

Preferred Qualifications

  • Familiar in R, additional solid debugging. experience in C/C/Java/Perl/Python/JavaScript/ReactJS;
  • Familiarity with workflow orchestration frameworks (Nextflow, Snakemake, Latch) or cloud computing and high-performance computing environments.
  • Fundamental understanding of assay development, PCR chemistry
  • Familiarity with cancer biology, genetics
  • Experience with other assay development platforms, such as NGS, microarrays, etc.
  • Hands-on experience with qPCR/dPCR instrumentation, assay optimization and validation.

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About Thermo Fisher

Thermo Fisher

Thermo Fisher Scientific Inc. is an American life science and clinical research company. It is a global supplier of analytical instruments, clinical development solutions, specialty diagnostics, laboratory, pharmaceutical and biotechnology services.

10,001+

Employees

Waltham

Headquarters

Reviews

3.9

2 reviews

Work Life Balance

3.5

Compensation

2.5

Culture

3.5

Career

4.0

Management

3.0

65%

Recommend to a Friend

Pros

Large company with extensive resources

Structured internship program

Career opportunities in product management

Cons

Low compensation ($22/hour)

High cost of living in location

Expensive housing/rent

Salary Ranges

2,260 data points

Mid/L4

Mid/L4 · Advanced Product Design Specialist

3 reports

$164,375

total / year

Base

$126,443

Stock

-

Bonus

-

$148,260

$164,375

Interview Experience

8 interviews

Difficulty

3.0

/ 5

Duration

14-28 weeks

Offer Rate

12%

Experience

Positive 12%

Neutral 63%

Negative 25%

Interview Process

1

Application Review

2

Recruiter Screen

3

Hiring Manager Interview

4

Panel Interview

5

Final Interview

6

Offer

Common Questions

Technical Knowledge

Behavioral/STAR

Past Experience

Culture Fit

Industry Specific