Use Your Power for Purpose

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. At the core of this mission is Research and Development, where we strive to transform advanced science and technologies into the most impactful therapies and vaccines. Whether you are involved in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will leverage cutting-edge design and process development capabilities. This collaborative effort accelerates the delivery of best-in-class medicines to patients globally, fulfilling Pfizer’s commitment to making a significant difference in healthcare.

What You Will Achieve

In this role, you will be part of Pharmaceutical Research and Development, supporting Pfizer’s biotherapeutics portfolio, which includes peptides, proteins, monoclonal antibodies (m Abs), antibody–drug conjugates (ADCs), vaccines, mRNA, and other biologics. You will contribute to the development of parenteral formulations across these modalities.

The position involves performing formulation development and analytical characterization of candidate molecules using a range of biophysical and biochemical techniques. You will also support drug product manufacturing process development and be responsible for data compilation, presentations, and technical report writing.

A strong foundation in scientific principles and best practices will enable you to meet critical deadlines and deliver high‑quality work. As a technical contributor, you will assess assigned tasks and make informed decisions through the direct application of your expertise. Your dedication will help Pfizer reach new milestones and ultimately improve the lives of patients worldwide.

How You Will Achieve It

The responsibilities of the Senior Associate Scientist position include, but are not limited to:

• Participate in the development of parenteral formulations for biotherapeutic modalities, including peptide‑based therapeutics, m Abs, ADCs, proteins, and vaccines. Under general supervision, support the development of associated drug product manufacturing processes.

• Perform rapid and comprehensive characterization of candidate molecules to establish stability profiles and apply these insights to develop appropriate dosage forms that meet clinical requirements. This work will utilize a broad range of biophysical and biochemical techniques, including UPLC (SE‑UPLC, IEX, RP‑UPLC), SDS‑PAGE, LC‑MS, capillary gel electrophoresis (CGE), imaged capillary electrophoresis (iCE), and spectroscopy methods such as UV, fluorescence, circular dichroism, and FTIR.

• Assist in the development and scale‑up of drug product processes from bench‑top to pilot scale, and, as required, support technology transfer to commercial manufacturing facilities. Drug product processes may include fluid handling, sterilizing filtration, and lyophilization.

• Collaborate effectively with a multidisciplinary team of scientists to support formulation optimization and overall candidate progression.

• Prepare data summary presentations, compile experimental data, and author technical reports to clearly communicate results and conclusions.

• Demonstrate effective communication skills when interacting with laboratory scientists, project managers, and cross‑functional colleagues while contributing to multidisciplinary project teams.

Here Is What You Need (Minimum Requirements)

• Bachelor’s degree (BA/BS) in Biochemistry, Chemical or Biochemical Engineering, Pharmacy, Chemistry, Biology, or a related discipline with 2–4 years of relevant experience, or a Master’s degree with 0–2 years of experience.

• Hands‑on laboratory experience with a variety of analytical techniques.

• Experience with analytical characterization of biotherapeutics using techniques such as UPLC (IEX), SDS‑PAGE, capillary gel electrophoresis (CGE), imaged capillary electrophoresis (iCE), and spectroscopic methods.

• Strong organizational and time‑management skills.

• Excellent oral and written communication skills.

• Proficiency with general computer software, including word processing, spreadsheets, and presentation tools.

• Demonstrated ability to solve scientific problems using contemporary experimental techniques.

• Experience accurately recording experimental details and data in an electronic laboratory notebook (ELN).

Bonus Points If You Have(Preferred Requirements)

• Master’s degree in a relevant scientific discipline.

• Experience in peptide synthesis, or peptide conjugation (including lipidated and/or chemically modified peptides), formulation development, or analytical characterization of peptides and peptide conjugates using techniques such as SE‑UPLC, RP‑UPLC, LC‑MS, peptide mapping, and related methods.

• In‑depth knowledge of current U.S. and global regulatory requirements, including FDA and ICH guidance.

• Familiarity with quality system regulations (21 CFR Part 4) for combination products.

• Ability to review, interpret, and approve engineering and development documentation.

• Strong collaboration skills and experience working effectively within multidisciplinary project teams.

• Excellent problem‑solving and critical‑thinking skills.

• Demonstrated ability to prioritize and manage work to meet project timelines and deadlines.

• Strong attention to detail and a high level of accuracy in scientific work and documentation.

• Experience using common AI‑enabled tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity.

PHYSICAL/MENTAL REQUIREMENTS:

This is a lab-based position and incumbent must be able to perform all lab-based duties

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Some travel expected to support work across other Pfizer sites or CMO/CDMO network.

Relocation support available
Work Location Assignment: On Premise

The annual base salary for this position ranges from $68,600.00 to $114,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

Research and Development: