Role Overview

The Senior CTMS Delivery Product Manager is responsible for technical delivery, system design coherence, and architectural integrity of the Salesforce-based Clinical Trial Management System (CTMS), including Cloudbyz components.

This role sits within the technology organization and serves as the technical design authority for CTMS delivery, ensuring that Clin Ops-owned business decisions and outcomes are implemented using a holistic, end-to-end system architecture that supports scalability, compliance, and long-term maintainability.

The role focuses on how CTMS changes are designed and delivered technically, while system roadmap and final business decisions remain with Clinical Operations, consistent with the CTMS governance model .

Key Responsibilities

CTMS Technical Architecture & System Design

(IT Delivery Accountability | Clin Ops Consulted)

Act as the CTMS Technical System Architect for Salesforce and Cloudbyz implementations

Maintain a holistic architectural view of the CTMS platform across:

Study, site, subject, and financial modules

Integrations with EDC, eTMF, IRT, ERP, and analytics systems

Evaluate proposed changes for cross-module, cross-study, and cross-system impacts

Define and enforce technical design standards, data models, and integration patterns

Prevent fragmented, study-specific configurations that introduce technical debt

Architectural accountability is technical delivery-focused and does not include ownership of business processes, system outcomes, or regulatory risk, which reside with Clin Ops .

CTMS Delivery & Execution

(IT Accountable | Cloudbyz Responsible under IT)

Serve as the IT delivery owner for CTMS enhancements and platform changes

Execute delivery against a Clin Ops-defined and approved CTMS roadmap

Manage Cloudbyz as an IT vendor, ensuring execution aligns with internal architectural standards

Lead Agile delivery activities including backlog refinement, sprint planning, and release execution

Balance configuration vs. customization decisions to support scalability and maintainability

Business Intake & Translation (Design-Governed)

(Clin Ops Accountable | IT Responsible for Translation)

Partner with Clinical Systems and business stakeholders to:

Review approved change requests from a system-design and delivery feasibility perspective

Translate requirements into technically sound user stories and acceptance criteria

Surface architectural risks and recommend alternative technical approaches when business requests may compromise system integrity or scalability

Salesforce Technical Leadership

(IT Responsible)

Provide technical product leadership across:

Salesforce configuration, customization, automation, and reporting

Cloudbyz CTMS modules and extensions

Coordinate and oversee integrations to ensure data consistency and architectural alignment

Collaborate with developers, architects, and vendors to ensure adherence to CTMS delivery standards

Compliance Support & Validation-Ready Delivery

(Quality Accountable | IT Supports)

Design and deliver CTMS changes that support:

GxP principles

21 CFR Part 11 requirements

Validation and audit readiness

Partner with Quality and Clinical Systems to support CSV activities, recognizing that validation accountability resides with Quality

Stakeholder Communication & Delivery Governance

(Shared Governance Model)

Communicate delivery status, architectural decisions, and technical risks to:

Clinical Systems leadership:

IT leadership

Serve as the escalation point for technical design and delivery conflicts

Proactively identify systemic design issues and delivery risks before they impact production or compliance

Required Qualifications

10+ years of experience in technical product management, system architecture, or enterprise application delivery

Hands-on experience designing and delivering Salesforce-based platforms

Strong experience with CTMS platforms

Proven ability to act as technical design authority while operating within a business-owned governance model

Experience in GxP-regulated environments with validated systems

Preferred Qualifications

Experience combining delivery ownership and system architecture responsibilities

Familiarity with EDC, eTMF, IRT, safety, and financial systems

Salesforce certifications (Admin, Platform App Builder, Integration Architecture Designer)

PMI Certification

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Austin, TX**$140,900—$176,100 USD**

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

• Competitive Benefits
• Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

*If you are based in California, we encourage you to read this important information for California residents. *

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:

• BBB announcement on job scams
• FBI Cyber Crime resource page