The Opportunity

We are seeking a visionary Senior AI Architect to pioneer the integration of cutting-edge AI solutions across our Salesforce CRM ecosystem and AWS cloud infrastructure. This is a strategic, high-impact role where you'll architect and implement Generative AI applications that transform how we engage with patients, automate complex workflows, and unlock predictive insights from our data.

You'll serve as our technical authority on the convergence of Salesforce Data Cloud, Einstein Trust Layer, and Amazon Bedrock, moving beyond simple integrations to build sophisticated "Bring Your Own Model" (BYOM) architectures that are secure, scalable, and measurably impactful.

What You'll Do

AI Strategy & Architecture (40%)

• Define end-to-end architecture for Generative AI solutions, integrating Salesforce Data Cloud with Amazon Bedrock and Sage Maker

• Design "Bring Your Own Model" (BYOM) patterns that enable Salesforce to securely access foundational models (Claude, Titan, Llama 2) hosted on AWS via Bedrock

• Architect data ingestion and grounding strategies using RAG (Retrieval Augmented Generation) to ensure AI models have real-time access to unified customer and patient profiles

• Establish comprehensive AI governance frameworks ensuring compliance with Einstein Trust Layer standards, including data privacy, zero-data retention policies, and PII masking

Implementation & Development (30%)

• Lead technical implementation of Model Builder and Prompt Builder within Salesforce, connecting them to external AWS endpoints

• Configure Amazon Bedrock agents and knowledge bases to execute complex tasks and retrieve proprietary data for business users

• Develop serverless middleware using AWS Lambda and API Gateway to enable low-latency communication between Salesforce Flow/Apex and AWS inference endpoints

• Oversee fine-tuning of models on AWS Sage Maker when out-of-the-box Bedrock models require domain-specific adaptation for healthcare use cases

Cross-Functional Collaboration (20%)

• Partner with Data Engineers to ensure Salesforce Data Cloud correctly ingests, harmonizes, and activates data streams from S3, Redshift, and other enterprise sources

• Collaborate with Salesforce Administrators and Developers to embed AI outputs directly into workflows (Service Console, Lightning Web Components, etc.)

• Serve as the AI subject matter expert for Product Managers, translating "AI buzzwords" into viable technical roadmaps and realistic, measurable deliverables

• Work closely with Business Systems leadership to align AI initiatives with strategic transformation goals

Optimization & Innovation (10%)

• Monitor LLM performance metrics including latency, accuracy, and token costs; implement caching strategies and intelligent model selection logic to optimize spend

• Stay ahead of rapid evolution in the Salesforce/AWS partnership, evaluating and piloting new capabilities like Zero Copy Data Sharing and Vector Database integrations

• Drive continuous improvement through A/B testing, performance benchmarking, and user feedback loops

What You'll Bring

Required Technical Expertise

AWS AI/ML Stack:

• Deep, hands-on expertise in Amazon Bedrock (mandatory)

• Proven experience configuring Bedrock Knowledge Bases, Agents, and Guardrails

• Proficiency with AWS Lambda, API Gateway, IAM, and security best practices for cross-cloud access

• Working knowledge of AWS Sage Maker for model training and deployment

Salesforce AI Stack:

• Strong working knowledge of Salesforce Data Cloud and Einstein 1 Platform

• Experience with Model Builder and Prompt Builder setup and configuration

• Understanding of Salesforce Service Cloud and Sales Cloud architecture

Architecture & Integration:

• Demonstrated experience designing RAG (Retrieval Augmented Generation) architectures

• Experience with Vector Database integrations (Open Search Serverless, Pinecone, or similar)

• Expert-level knowledge of REST/gRPC APIs, OAuth 2.0 flows, and named credentials for secure Salesforce-to-AWS connectivity

Programming:

• Proficiency in Python (AWS Lambda, Boto3, data processing)

• Familiarity with Apex for Salesforce triggers, callouts, and custom logic

• Experience with Infrastructure as Code (Terraform, CloudFormation) is a plus

Experience Requirements

• 8+ years of experience in Enterprise Architecture, Cloud Engineering, or Data Science roles

• 3+ years specifically focused on AI/ML solution design or Data Engineering

• Proven track record of deploying at least one Generative AI solution into production (not just POCs or demos)

• Experience implementing "Zero Copy" architecture between Salesforce and Data Warehouses (Snowflake, Redshift) is highly desirable

• Healthcare or regulated industry experience is a plus

Preferred Certifications

• AWS Certified Solutions Architect – Professional

• AWS Certified Machine Learning – Specialty

• Salesforce Data Cloud Consultant or AI Associate

• Salesforce Certified Application Architect or System Architect

Knowledge, Skills & Abilities

LLM Fluency: Deep understanding of how large language models work, including context windows, prompt engineering techniques (Chain of Thought, Re Act, few-shot learning), embeddings, and vector search.

Security-First Mindset: A healthy paranoia for security—understanding how to prevent prompt injection attacks, ensure data residency compliance when data leaves Salesforce for AWS, and implement zero-trust architectures.

Strategic Communication: The ability to explain complex AI concepts to non-technical stakeholders—including C-suite executives—in clear, compelling terms without losing their attention or oversimplifying critical details.

Problem-Solving: Ability to navigate ambiguity, make architectural trade-offs, and balance innovation with pragmatic delivery in a fast-paced healthcare environment.

Collaboration: Experience working across technical and business teams, building consensus, and driving adoption of new technologies.

Why Join Natera

• Impact: Your work will directly improve patient experiences and healthcare outcomes for thousands of families

• Innovation: Work at the cutting edge of AI in healthcare, with access to the latest tools and technologies

• Growth: Join a rapidly scaling organization with significant investment in AI and digital transformation

• Leadership: Work alongside experienced technology leaders from Google, Meta, and other top tech companies

• Culture: Collaborative, mission-driven environment that values continuous learning and technical excellence

Compensation & Benefits

Natera offers competitive compensation including base salary, performance bonuses, and equity. We provide comprehensive benefits including health insurance, 401(k) matching, flexible PTO, professional development budget, and more.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Austin, TX**$152,800—$191,000 USD**

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

• Competitive Benefits
• Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

*If you are based in California, we encourage you to read this important information for California residents. *

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:

• BBB announcement on job scams
• FBI Cyber Crime resource page