Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

Responsibilities

Sets up and performs routine and established lab procedures in support of lab goals, grant commitments, i.e. assays, cell/tissue culture, animal studies, etc. Monitors results, reports unusual outcomes and suggests modifications. Collects, enters and summarizes data. Assists in the maintenance of lab equipment and supplies. Performs basic statistical data analysis; prepares tables/charts/graphs and assists in organizing data. Presents at research laboratory meetings and contributes to writing of manuscripts. Works under supervision and may perform some assignments independently as discussed and approved by Principal Investigator.

This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.

Additional Information:

The Lomberk Laboratory is seeking a Research Technician who takes pride in rigorous science and is eager to develop their skills within a collaborative, discovery-driven research environment. This position is well-suited for candidates looking to build a strong technical foundation in cellular and molecular biology while contributing to meaningful, translational research.

About the Lab

The Lomberk Laboratory investigates how epigenomic regulators, including chromatin-modifying enzymes and remodeling complexes, control gene expression programs downstream of oncogenic signaling, shape DNA damage responses, and drive disease progression in cancers such as pancreatic cancer. Our work spans mechanistic discovery to translational impact, using cell-based assays, patient-derived model systems, and mouse models to identify vulnerabilities that can be targeted therapeutically.

Purpose

Under general direction from laboratory leadership, the Research Technician will perform, optimize, and implement a variety of laboratory techniques and experiments to support the generation of high-quality data in a cellular and molecular biology research setting. The individual will analyze, summarize, and present data to a team of scientists and contribute to discussions guiding next steps in research projects.

Responsibilities May Include:

• Perform protein-based assays including immunoblotting, co-immunoprecipitation, and chromatin immunoprecipitation (ChIP) to interrogate epigenomic and signaling pathways
• Execute biochemical approaches to characterize protein-protein interactions and structure-function relationships of epigenomic regulators
• Maintain mammalian cell lines and execute functional cell-based assays
• Perform pharmacological assays to assess cellular responses to targeted therapies, epigenetic modulators, and their combinations
• Perform immunofluorescence microscopy and imaging-based assays to assess DNA damage responses, chromatin organization, and nuclear architecture
• Perform standard molecular biology techniques in support of ongoing projects
• Assist with laboratory mouse work, including colony maintenance, genotyping, and support of experimental studies
• Execute established protocols and assist in optimizing and scaling experimental procedures as needed
• Maintain accurate and organized records of experimental procedures and results
• Support day-to-day laboratory operations, including reagent and media preparation, supply monitoring, inventory management, and ordering
• Participate in laboratory meetings and contribute to the evaluation and interpretation of experimental data
• Assist in preparation of figures, methods, and other materials for manuscripts and presentations

We Are Looking for a Candidate Who:

• Has a background in biology, biochemistry, or a related field
• Has experience with or familiarity in cell culture, protein assays, or other core molecular biology techniques
• Demonstrates strong attention to detail, organization, and reliability in experimental work
• Is comfortable assisting with mouse work and general laboratory responsibilities
• Possesses strong written and verbal communication skills
• Is motivated, collegial, and able to work effectively in a team-oriented environment
• Is eager to learn and grow in a research setting

Why Join Us?

• Receive hands-on training and mentorship in epigenomics and disease-focused research
• Work in a collaborative and interdisciplinary environment at the forefront of cancer and inflammatory disease biology
• Contribute to studies with direct relevance to therapeutic development
• Build technical skills with real opportunities for increased responsibility and longer-term growth within the laboratory
• Contribute to scientific outputs including publications and presentations

Qualifications

Requires bachelor's degree in biology, chemistry, other relevant science, or an associates degree with 6 years of relevant laboratory experience. Must exhibit a solid understanding of lab techniques, equipment, and safety. Must have the ability to organize and carry out laboratory techniques independently and in a team setting. Experience with basic data analysis is required. This position requires demonstrated writing skills.

Exemption Status

Nonexempt

Compensation Detail

$27.99 - $41.98 /hr Experience and tenure may be considered along with internal equity when job offers are extended.

Benefits Eligible

No

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

• Monday
• Friday (Normal Business Hours)

Weekend Schedule

Rare weekend work pending needs of research.

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'. Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Recruiter

Matt Burdick