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Job Summary

About the Gene and Cell Therapy Institute (GCTI) - The Gene and Cell Therapy Institute (GCTI) at Mass General Brigham advances the development and translation of transformative genetic medicines. The Institute brings together leading investigators, clinicians, and industry partners to accelerate innovation across gene therapy, genome editing, and cell-based therapies. Through integrated platforms, translational programs, and strategic collaborations, GCTI is focused on delivering scalable, impactful therapies to patients.

• Role Summary
• The Project Manager will support complex, multi-institutional programs, with a primary focus on ARPA-H–funded initiatives, while also contributing across broader GCTI programs and strategic initiatives. This role will coordinate across scientific and operational teams to ensure alignment with milestone-driven objectives, while maintaining flexibility to adapt across evolving roles and priorities as GCTI needs shift.

The Project Manager will partner closely with program leadership, investigators, and collaborators to support execution, maintain accountability, and enable the successful delivery of high-impact programs across the Institute.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

Project Management & Execution (Multi-Institutional ARPA-H Programs)

-Lead day-to-day coordination and execution of a multi-institutional ARPA-H THRIVE program focused on neurovascular applications of genome editing, ensuring alignment with aggressive milestones, timelines, and deliverables
-Develop and maintain integrated project plans, including dependencies, to drive execution toward clinical development milestones
-Coordinate meetings with internal teams, sub-performers, and external collaborators to ensure alignment, accountability, and timely execution
-Manage meeting agendas, and action tracking across committees and stakeholders
-Prepare and manage program deliverables, including ARPA-H reports, milestone updates, and internal briefings
-Maintain centralized trackers, dashboards, and documentation to support program transparency
-Monitor performance, and support mitigation strategies; escalate issues to leadership as needed to maintain program momentum

Communications, Events & External Engagement

-Support institute-wide communications, including marketing emails, newsletters, and digital content, while maintaining web and online platforms to ensure content is current and aligned with Institute branding
-Aid the coordination, planning and execution of key events, including the Annual Symposium and monthly hybrid seminar series
-Manage stakeholder communications, conference materials, and program content

GCTI Programs & Broader Strategic Initiatives:

-Support cross-institute programs, new funding initiatives, and program launches aligned with GCTI priorities
-Contribute to portfolio tracking, internal reporting, and synthesis of program outcomes across different initiatives
-Provide flexible support for Institute-wide priorities, including collaborations and strategic efforts

QualificationsQUALIFICATIONS:

• Bachelors degree required (experience can be considered in lieu of a degree); Advanced degree (PhD) in life sciences, biomedical sciences, gene editing, or a relevant gene therapy-related discipline highly preferred
• At least 2-3 years of program management experience required
• Minimum of 1 year of experience in life science consulting, project management highly preferred Preferred Qualifications
• Experience supporting federally funded programs (e.g., ARPA-H, NIH, DARPA)
• Domain expertise in genome editing, neuroscience, CNS, cardiovascular, or vascular biology
• Experience working across academia–industry collaborations
• Experience within an academic medical center or university setting, with a strong scientific foundation

SKILLS/ABILITIES/COMPETENCIES:

• Demonstrated ability to manage multiple projects and competing priorities in a fast-paced, cross-functional environment
• Ability to collaborate effectively with academic investigators and industry partners
• Familiarity with translational research and/or clinical development processes
• Demonstrated ability to operate independently (ability to own the projects) while effectively coordinating across multidisciplinary teams, including faculty, institutional leadership, and external partners
• Highly organized and detail-oriented, with the ability to manage multiple priorities, adapt to shifting timelines, and deliver under pressure
• Excellent written and verbal communication skills
• Ability to translate complex scientific concepts into clear, accessible communications for varied audiences
• Strong stakeholder management skills and ability to drive discussions
• Proven problem-solving and analytical capabilities, with sound judgment in navigating complex, fast-paced program environments
• Comfortable working in dynamic environments with a high degree of ambiguity
• Proficiency in Microsoft Office, including Excel and program management tools
• Demonstrated discretion in handling sensitive and confidential information

Additional Job Details (if applicable)Working Conditions:

• This is an onsite role, mostly at the GCTI offices with occasional team meetings at MGH

Remote Type

Onsite

Work Location

65 Landsdowne Street

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

Pay Range

$63,648.00 - $90,750.40/Annual

Grade

6

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement:

0100 Mass General Brigham Incorporated is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.