Site: The Brigham and Women's Hospital, Inc.

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Job Summary

Join the Santagata Lab at Brigham and Women’s Hospital (BWH) as a Technical Research Assistant I.

We are seeking a talented and highly motivated individual to join our team in using cutting-edge molecular tissue imaging and quantitative assay methods to study tumor development, therapy resistance, and disease mechanisms in patient samples across a range of cancers. This role offers an outstanding opportunity to work at the interface of biological chemistry, molecular imaging, and clinical research, contributing to the development of new cancer therapies and diagnostics.

Qualifications

• You will be based in Dr. Sandro Santagata’s laboratory and collaborate closely with Dr. Peter Sorger’s multidisciplinary team at Harvard Medical School’s (HMS) Laboratory of Systems Pharmacology (LSP) (https://www.tissue-atlas.org/), as well as with members of Ludwig Cancer Research, the David Liposarcoma Research Initiative, the Bertarelli Rare Cancer Initiative and the Pituitary Neuroendocrine Tumor Translational Research (BioPitNeT).

• Engage with a vibrant network of scientists, physicians, chemists, and computational biologists across institutions including BWH, HMS, Massachusetts General Hospital, Dana-Farber Cancer Institute, Boston Children’s Hospital, and the Ludwig Center at Harvard, as well as collaborators nationwide.

• Contribute directly to research that informs innovative clinical trials for immunotherapy and targeted therapies for sarcomas, gliomas, carcinomas, and neuroendocrine-related tumors. Investigate disease mechanisms and pharmacodynamics (PD) to support biomarker and drug development. Opportunities are also available to participate in studies of pulmonary and renal diseases.

This is an outstanding opportunity to be part of a dynamic, multidisciplinary team at the forefront of quantitative biology and translational pathology. You will gain hands-on experience with high-dimensional pathology imaging, molecular assay development, data processing, computational analysis, and visualization, while contributing to high-impact translational research that can change how cancers and other diseases are diagnosed and treated.

If you are a self-motivated individual with a passion for innovative biomedical research and collaborative projects, we encourage you to apply and become a key member of our vibrant team.

Additional Job Details (if applicable)

Qualifications:

• Bachelor’s degree in a quantitative discipline, such as chemistry, biological chemistry, chemical biology, biophysics, biomedical engineering, or a related field.
• Demonstrated interest in biomedical research, molecular measurement, and human disease.
• Willingness to commit to a two-year position and grow in a dynamic research environment.

Skills/Abilities/Competencies Required:

• Experience or strong interest in microscopy, molecular or biochemical assays, quantitative biology, or data analysis is highly valued.
• Strong background in biochemistry or biological chemistry, including understanding of protein structure–function relationships, antibody–antigen interactions, and molecular binding principles, is important for the design, optimization, and interpretation of multiplexed tissue imaging assays.
• Familiarity with or interest in quantitative image analysis and data science tools (e.g., Python, R, MATLAB, ImageJ) is preferred.
• Strong communication skills and the ability to work both independently and collaboratively within a multidisciplinary research team.

Remote Type

Onsite

Work Location

60 Fenwood Road

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

Pay Range

$20.16 - $29.01/Hourly

Grade

5

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement:

2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.