JLL empowers you to shape a brighter way.

Our people at JLL are shaping the future of real estate for a better world by combining world class services, advisory and technology for our clients. We are committed to hiring the best, most talented people and empowering them to thrive, grow meaningful careers and to find a place where they belong. Whether you’ve got deep experience in commercial real estate, skilled trades or technology, or you’re looking to apply your relevant experience to a new industry, join our team as we help shape a brighter way forward.

Position Overview

Senior Project Manager

Responsible for the end-to-end delivery of life sciences capital projects, including GxP facility renovations (minor and major), new laboratory/manufacturing builds, and critical utility infrastructure upgrades. This role ensures all projects maintain a "state of control" and meet stringent regulatory requirements.

Essential Requirements

Education & Certifications

• Bachelor’s degree in Engineering (Mechanical, Chemical, or Civil), Construction Management, Architecture, or a related scientific field.

• PMP (Project Management Professional) certification required.

• **ISPE (International Society for Pharmaceutical Engineering)**membership or LEED AP certification is highly advantageous.

Experience

• 7–10 years of project management experience in complex technical construction.

• 5+ years of specific experience in Life Sciences, Biotech, or Pharmaceutical environments.

• Proven track record managing GMP facility capital projects($1M–$25M+), including cleanroom build-outs (ISO 5–8), laboratory renovations, and critical infrastructure (validated HVAC, WFI/RO high-purity water, and EMS).

• Expertise in overseeing the technical integration of manufacturing skids, analytical instrumentation, and specialized containment areas (e.g., BSL-2/3).

• Deep understanding of **FDA (21 CFR Part 211)**and EMA regulatory requirements.

• Experience interfacing with local authorities, including zoning and specialized fire/safety code officials for hazardous material storage.

Technical Competencies

Project Management & Validation

• Validation & Commissioning:

Mastery of the V-Model approach, including IQ/OQ/PQ protocols and Turnover Packages (TOP).

• Quality Management Systems (QMS):

Direct experience managing Change Controls, Deviations, and CAPAs within a regulated project lifecycle.

• Scheduling & Cost Control:

Proficiency in MS Project or Primavera P6; expertise in budget forecasting and mitigating "scope creep" in highly regulated environments.

• Risk Management:

Ability to perform FMEA (Failure Mode and Effects Analysis) to protect product integrity during construction.

Technical Knowledge & Compliance

• Cleanroom Standards:

In-depth knowledge of ISO 14644 standards and Grade A–D operational requirements.

• Operational Workflows:

Understanding of unidirectional flow for personnel, material, and waste to prevent cross-contamination.

• Technical Skills:

Proficiency in BIM/VDC platforms (Autodesk Construction Cloud, Procore) and document control for audit-ready project files.

Core Competencies

Leadership & Communication

• Cross-Functional Leadership:

Ability to lead teams of MEP engineers, Validation specialists, QA/QC officers, and Architects of Record.

• Executive Presence:

Ability to present project risks and financial health to C-suite stakeholders and Steering Committees.

• Conflict Resolution:

Skill in negotiating with specialized sub-contractors and vendors (e.g., orbital welders, cleanroom panel installers).

Analytical & Problem-Solving

• Critical Decision Making:

Ability to assess if a construction delay or field change impacts the validated state of the facility.

• Process Improvement:

Applying "Lean Construction" or specialized methodologies to minimize downtime during facility shutdowns.

Preferred Qualifications

• Experience with Brownfield projects (renovating active GMP facilities without interrupting production).

• Familiarity with Digital Plant initiatives (Smart Buildings, IoT sensors for monitoring, and Lab Automation).

Key Performance Indicators (KPIs)

• On-Time Delivery:

Target 95%+ (aligned with manufacturing production schedules).

• Budget Adherence:

100% within approved budget, including management of contingency.

• Validation Success Rate:

Zero "Major" findings during Quality/Regulatory audits of project files.

• Safety Record:

Zero lost-time incidents; 100% compliance with site-specific EHS protocols.

• Quality Metrics:

Successful transition from "Mechanical Completion" to "Operational Readiness" with minimal punch-list items.

This position does not provide visa sponsorship. Candidates must be authorized to work in the United States without sponsorship.

Estimated compensation for this position:

110,000.00 – 150,000.00 USD per year

This range is an estimate and actual compensation may differ. Final compensation packages are determined by various considerations including but not limited to candidate qualifications, location, market conditions, and internal considerations.

Location:

On-site –South San Francisco, CA

If this job description resonates with you, we encourage you to apply, even if you don’t meet all the requirements. We’re interested in getting to know you and what you bring to the table!

Personalized benefits that support personal well-being and growth:

JLL recognizes the impact that the workplace can have on your wellness, so we offer a supportive culture and comprehensive benefits package that prioritizes mental, physical and emotional health. Some of these benefits may include:

• 401(k) plan with matching company contributions

• Comprehensive Medical, Dental & Vision Care

• Paid parental leave at 100% of salary

• Paid Time Off and Company Holidays

• Early access to earned wages through Daily Pay

At JLL, we harness the power of artificial intelligence (AI) to efficiently accelerate meaningful connections between candidates and opportunities. Using AI capabilities, we analyze your application for relevant skills, experiences, and qualifications to generate valuable insights about how your unique profile aligns with the specific requirements of the role you're pursuing.

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For candidates in the United States, please see a full copy of our Equal Employment Opportunity policy here.

Jones Lang LaSalle (“JLL”) is an Equal Opportunity Employer and is committed to working with and providing reasonable accommodations to individuals with disabilities. If you need a reasonable accommodation because of a disability for any part of the employment process – including the online application and/or overall selection process – you may email us at HRSCLeaves@jll.com. This email is only to request an accommodation. Please direct any other general recruiting inquiries to our Contact Us page > I want to work for JLL.

Pursuant to the Arizona Civil Rights Act, criminal convictions are not an absolute bar to employment.

Pursuant to Illinois Law, applicants are not obligated to disclose sealed or expunged records of conviction or arrest.

Pursuant to Columbia, SC ordinance, this position is subject to a background check for any convictions directly related to its duties and responsibilities. Only job-related convictions will be considered and will not automatically disqualify the candidate.

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Pursuant to the Los Angeles Fair Chance Initiative for Hiring Ordinance, JLL will consider for employment all qualified Applicants, including those with Criminal Histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance.

Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

Accepting applications on an ongoing basis until candidate identified.