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Principal Scientist, In Vitro Metabolism (1805127)

IQVIA

Principal Scientist, In Vitro Metabolism (1805127)

IQVIA

Indianapolis, Indiana, United States of America

·

On-site

·

Full-time

·

1w ago

Compensation

$89,000 - $206,700

Benefits & Perks

Healthcare

Mental Health

Healthcare

Mental Health

Required Skills

In vitro ADME

CYP assays

Protein binding

Method development

Data analysis

Scientific communication

We are seeking Principal Scientist, In Vitro Drug Metabolism to join IQVIA Laboratories at Indiana.

We hire passionate innovators who drive healthcare forward through thoughtful and inclusive collaboration. If you want to discover a career with greater purpose, join us as we transform and accelerate research and development.

Job Summary:

This role provides scientific leadership in complex in vitro drug metabolism method development and supports clients across the drug development lifecycle, including IND‑enabling studies. The Principal Scientist independently designs and executes assays, interprets data, and delivers high‑quality client-facing outputs.

What You’ll Be Doing:

  • Design and execute complex in vitro drug metabolism studies, including CYP, UGT, AO, FMO, metabolic clearance, and protein binding assays
  • Serve as Principal Investigator on client studies and ensure clear communication of progress and results
  • Develop, implement, and optimize new in vitro methods for client programs
  • Prepare technical summaries, study protocols, and high-quality reports suitable for regulatory submission
  • Lead multiple technical projects while guiding junior scientists in daily laboratory activities

What We Are Looking For:

  • Bachelor’s degree in biology, chemistry, or related field with 7+ years of in vitro ADME experience; OR a Master’s with 4+ years; OR a recent Ph.D. with relevant in vitro metabolism training.
  • Hands‑on experience with in vitro ADME assays, including CYP inhibition/induction/phenotyping and protein binding
  • Industry experience within a pharmaceutical ADME group or a CRO supporting IND‑enabling studies
  • Technical proficiency with in vitro method development and related analytical tools
  • Other Equivalent combination of education, training, and experience may be accepted in lieu of degree

The Knowledge, Skills and Abilities Needed for This Role:

  • Ability to independently manage multiple complex scientific projects
  • Strong data analysis, interpretation, and scientific communication skills
  • Proficiency with Microsoft Excel, scientific software, and electronic lab documentation systems

What We Offer You:

We put our employees at the center of everything we do and are committed to providing them, and their families, with benefits that meet their diverse and changing needs. We invest in integrated benefits programs and resources to take care of our employees’ physical, mental and emotional, financial and social well-being so they can thrive at home and at work, at any stage of their well-being journey.To learn more about our benefits, visit https://jobs.iqvia.com/benefits.If you’re looking to unleash your potential, join IQVIA Laboratories to help make the extraordinary possible!

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com

IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.

The potential base pay range for this role, when annualized, is $89,000.00 - $206,700.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.

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About IQVIA

IQVIA

IQVIA

Public

Focused on health information technology and clinical research.

10,001+

Employees

Durham

Headquarters

$17B

Valuation

Reviews

3.9

2 reviews

Work Life Balance

2.5

Compensation

2.0

Culture

2.8

Career

3.0

Management

2.5

65%

Recommend to a Friend

Pros

Structured feedback and development process

Meaningful contribution to client businesses

Problem-solving with specialized knowledge

Cons

Strict performance requirements and termination risk

High-level rubric definitions lack detail

No performance bonuses offered

Salary Ranges

42 data points

Junior/L3

Senior/L5

Junior/L3 · Analyst

2 reports

$107,910

total / year

Base

$93,834

Stock

-

Bonus

-

$97,750

$118,068

Interview Experience

3 interviews

Difficulty

3.0

/ 5

Duration

14-28 weeks

Experience

Positive 0%

Neutral 33%

Negative 67%

Interview Process

1

Application Review

2

HR Screen

3

Hiring Manager Interview

4

Technical Manager Interview

5

Executive/GM Interview

6

Offer

Common Questions

Behavioral/STAR

Case Study

Technical Knowledge

Past Experience

Culture Fit