Jobs

Principal Scientist, In Vitro Metabolism (1805127)
Indianapolis, Indiana, United States of America
·
On-site
·
Full-time
·
1w ago
Compensation
$89,000 - $206,700
Benefits & Perks
•Healthcare
•Mental Health
•Healthcare
•Mental Health
Required Skills
In vitro ADME
CYP assays
Protein binding
Method development
Data analysis
Scientific communication
We are seeking Principal Scientist, In Vitro Drug Metabolism to join IQVIA Laboratories at Indiana.
We hire passionate innovators who drive healthcare forward through thoughtful and inclusive collaboration. If you want to discover a career with greater purpose, join us as we transform and accelerate research and development.
Job Summary:
This role provides scientific leadership in complex in vitro drug metabolism method development and supports clients across the drug development lifecycle, including IND‑enabling studies. The Principal Scientist independently designs and executes assays, interprets data, and delivers high‑quality client-facing outputs.
What You’ll Be Doing:
- Design and execute complex in vitro drug metabolism studies, including CYP, UGT, AO, FMO, metabolic clearance, and protein binding assays
- Serve as Principal Investigator on client studies and ensure clear communication of progress and results
- Develop, implement, and optimize new in vitro methods for client programs
- Prepare technical summaries, study protocols, and high-quality reports suitable for regulatory submission
- Lead multiple technical projects while guiding junior scientists in daily laboratory activities
What We Are Looking For:
- Bachelor’s degree in biology, chemistry, or related field with 7+ years of in vitro ADME experience; OR a Master’s with 4+ years; OR a recent Ph.D. with relevant in vitro metabolism training.
- Hands‑on experience with in vitro ADME assays, including CYP inhibition/induction/phenotyping and protein binding
- Industry experience within a pharmaceutical ADME group or a CRO supporting IND‑enabling studies
- Technical proficiency with in vitro method development and related analytical tools
- Other Equivalent combination of education, training, and experience may be accepted in lieu of degree
The Knowledge, Skills and Abilities Needed for This Role:
- Ability to independently manage multiple complex scientific projects
- Strong data analysis, interpretation, and scientific communication skills
- Proficiency with Microsoft Excel, scientific software, and electronic lab documentation systems
What We Offer You:
We put our employees at the center of everything we do and are committed to providing them, and their families, with benefits that meet their diverse and changing needs. We invest in integrated benefits programs and resources to take care of our employees’ physical, mental and emotional, financial and social well-being so they can thrive at home and at work, at any stage of their well-being journey.To learn more about our benefits, visit https://jobs.iqvia.com/benefits.If you’re looking to unleash your potential, join IQVIA Laboratories to help make the extraordinary possible!
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com
IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe
IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.
The potential base pay range for this role, when annualized, is $89,000.00 - $206,700.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.
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About IQVIA

IQVIA
PublicFocused on health information technology and clinical research.
10,001+
Employees
Durham
Headquarters
$17B
Valuation
Reviews
3.9
2 reviews
Work Life Balance
2.5
Compensation
2.0
Culture
2.8
Career
3.0
Management
2.5
65%
Recommend to a Friend
Pros
Structured feedback and development process
Meaningful contribution to client businesses
Problem-solving with specialized knowledge
Cons
Strict performance requirements and termination risk
High-level rubric definitions lack detail
No performance bonuses offered
Salary Ranges
42 data points
Junior/L3
Senior/L5
Junior/L3 · Analyst
2 reports
$107,910
total / year
Base
$93,834
Stock
-
Bonus
-
$97,750
$118,068
Interview Experience
3 interviews
Difficulty
3.0
/ 5
Duration
14-28 weeks
Experience
Positive 0%
Neutral 33%
Negative 67%
Interview Process
1
Application Review
2
HR Screen
3
Hiring Manager Interview
4
Technical Manager Interview
5
Executive/GM Interview
6
Offer
Common Questions
Behavioral/STAR
Case Study
Technical Knowledge
Past Experience
Culture Fit
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