Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

GRAIL is seeking a mission-driven and high-impact Staff Product Security Engineer to serve as a technical cornerstone for product security initiatives across the company. Reporting to the Director of Product Security, this role plays a critical part in enabling secure, resilient products that support GRAIL’s life‑saving mission.
As a Staff-level individual contributor, you will lead the technical execution of the Product Security roadmap, partner closely with Engineering and Product teams, and mentor other security engineers. You will influence architecture and development decisions across the product lifecycle, helping teams navigate an evolving threat landscape while maintaining delivery velocity in a regulated environment.

Flexible – Menlo Park (MPK) – 3 days in office
This role is based in Menlo Park, California, and will move to Sunnyvale, California in Fall 2026. GRAIL offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site.