At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Eli Lilly and Company seeks a Chemist (R1-R5) to perform quantitative analysis in support of RNA therapeutics development. Identify metabolites of oligonucleotides using high resolution mass spectrometry and liquid chromatography-mass spectrometry. Design and conduct in vitro and in vivo studies to assess siRNA-based modalities for efficacy, exposure, potency, and durability. Enable platform development through in vitro stability assays. Conduct analytical assay development for siRNA-based modalities in connection with pre-portfolio, portfolio, and candidate selection. Develop analytical methods to support antibody conjugated-siRNA programs. Develop alternative methods for tissue homogenization to improve throughput and sensitivity.

Position requires a Bachelor’s degree in Chemistry, Biochemistry, Pharmaceutical Science, or a related field, and 3 years of experience with performing quantitative biochemical analyses in an industrial or research organization setting. Experience must include a minimum of: 3 years of experience with leveraging high-performance liquid chromatography-mass spectrometry (HPLC-MS) for bioanalysis; 3 years of experience with high-resolution mass spectrometry tools, including Orbitrap/TOF; 3 years of experience with handling biological tissues and fluids in a research laboratory setting; and 3 years of experience with conducting oligonucleotide bioanalysis. Up to 5% domestic and international travel required.

Job location: Boston, MA.

To apply, please visit https://jobsearch.lilly.com/ and enter job requisition number R-103511 when prompted. Alternatively, please send your resume, cover letter, and a copy of the ad to: Matthew Tenaglio, Lilly Corporate Center, Indianapolis, IN 46285.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$128,773.00 - $187,000.00 per year

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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