About This Role:

As a Clinical Biomarker Senior Scientist, you will play a pivotal role in supporting the design, execution, and interpretation of biomarker activities across our clinical studies. You will work cross-functionally with Translational Research, Clinical Study Teams, and external labs/CROs to ensure the generation of high-quality biomarker data and its timely delivery to inform critical program decisions. This role is integral to aligning study activities with program biomarker strategies, helping to monitor early responses, generate insights into mechanisms of action, and understand resistance mechanisms. Your contributions will be essential to advancing our understanding of immune-mediated diseases and enhancing our clinical trial outcomes. Positioned within a highly matrixed environment, you will drive scientific and technical innovation, significantly contributing to the overall success of our projects.

What You’ll Do:

· Ensure alignment of study activities with program biomarker strategy to support early response monitoring and understanding of resistance mechanisms.

· Support biomarker implementation for clinical trials of immune-mediated diseases, providing strategic oversight to study-related documents.

· Analyze and interpret biomarker data in collaboration with computational biomarker data scientists.

· Translate preclinical findings into clinically actionable biomarker hypotheses.

· Oversee biomarker assay development, validation, and sample analysis with internal teams and external CROs.

· Collaborate in vendor selection, qualification, and tech transfer of biomarker assays with internal SMEs and external labs.

· Stay current with emerging biomarker technologies and trends in immune-mediated diseases.

· Identify and probe external datasets to inform clinical biomarker strategy.

· Support strategic initiatives by providing deep scientific knowledge of inflammatory pathways and mechanisms.

· Work effectively in a highly matrixed environment to drive scientific and technical innovation.

Who You Are:

You are a highly organized and collaborative scientist with a passion for biomarker research. Your strong communication skills enable you to work effectively with diverse teams, and you thrive in a matrixed environment where innovation is key. You bring a deep understanding of inflammatory pathways and mechanisms, complemented by hands-on experience in clinical biomarker modalities such as flow cytometry, NGS, or proteomics. Your ability to manage multiple studies and vendors showcases your exceptional organizational skills, making you a valuable asset in driving our scientific initiatives forward.

Required Skills:

· PhD and/or post-doc in immunology, molecular/cellular biology, biomedical engineering, pharmacology, or related field.

· 2+ years of experience in industry biomarker/translational work (biotech/pharma or CRO).

· Hands-on familiarity with at least one core clinical biomarker modality (e.g., flow cytometry, NGS, proteomics) and associated data QC.

· Strong organizational skills with demonstrated ability to manage multiple studies and vendors.

· Strong communications skills.

· Comfortable in a matrix environment.

Preferred Skills:

· Experience supporting clinical trials and working with external labs/CROs.

· Therapeutic area experience aligned to the portfolio (e.g., immunology/IMIDs, nephrology).

Job Level: Management

Additional Information:

The base compensation range for this role is: $123,000.00-$164,000.00
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to:

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.