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Principal Machine Learning Engineer

Amgen

Principal Machine Learning Engineer

Amgen

India - Hyderabad

·

On-site

·

Full-time

·

1mo ago

Benefits and perks

Healthcare

401(k)

Equity

Remote Work

Flexible Hours

Learning

Required skills

Python

Machine Learning

TensorFlow

PyTorch

Scikit-learn

MLOps

Leadership

Career Category

Information Systems:

Job Description

The AI/ML Lead will head Amgen’s AI/ML practice within the Innovation Lab, driving the development, validation, and deployment of machine learning and GenAI solutions across R&D, Manufacturing, and Commercial domains.

This role requires strong technical depth, leadership skills, and a deep understanding of responsible AI frameworks within regulated environments.

Key Responsibilities:

  • Lead AI/ML strategy and implementation across multiple Po Ds in the Innovation Lab.
  • Translate Amgen’s business objectives into data-driven AI/ML initiatives.
  • Define architecture, standards, and best practices for model design, training, and validation.
  • Oversee MLOps and CI/CD integration to enable scalable model deployment.
  • Guide the team on data preparation, feature engineering, and experimentation.
  • Review and approve model validation reports, metrics, and explainability artifacts.
  • Ensure compliance with Responsible AI, GxP, and privacy frameworks.
  • Collaborate with SMEs and Data Governance leads to align models with business and ethical objectives.
  • Mentor engineers, fostering innovation and technical excellence.

Required Qualifications

  • 10–15 years of experience in data science or machine learning engineering.
  • Proven leadership in AI/ML project delivery and technical governance.
  • Expertise in Python, Tensor Flow, Py Torch, Scikit-learn, or similar ML frameworks.
  • Experience with MLOps, MLflow, Databricks, and AWS Sage Maker.
  • Strong grounding in model lifecycle management and validation documentation.
  • Excellent analytical, communication, and cross-functional collaboration skills.

Preferred Skills

  • Experience with GenAI / LLM architectures (Lang Chain, OpenAI APIs, Hugging Face).
  • Prior exposure to pharma, biotech, or life sciences R&D.
  • Certification in Machine Learning / Data Science / AWS AI Specialist.
  • Familiarity with data privacy regulations (HIPAA, GDPR) and ethical AI standards.

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About Amgen

Amgen

Amgen

Public

A biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.

10,001+

Employees

Thousand Oaks

Headquarters

$138B

Valuation

Reviews

3.6

10 reviews

Work-life balance

3.2

Compensation

4.1

Culture

3.4

Career

2.8

Management

3.5

65%

Recommend to a friend

Pros

Excellent benefits and health benefits

Good pay and compensation

Supportive management and strong leadership

Cons

Limited career growth and promotion opportunities

Work-life balance challenges and long hours

Bureaucratic processes

Salary Ranges

1,244 data points

Junior/L3

L2

L3

L4

L5

L6

M3

M4

M5

M6

Mid/L4

Senior/L5

Staff/L6

Junior/L3 · Data Scientist

0 reports

$100,368

total per year

Base

-

Stock

-

Bonus

-

$85,234

$115,502

Interview experience

5 interviews

Difficulty

3.0

/ 5

Duration

14-28 weeks

Offer rate

40%

Experience

Positive 20%

Neutral 80%

Negative 0%

Interview process

1

Application Review

2

HR Screen

3

Hiring Manager Interview

4

Technical/Role-Specific Interview

5

Panel Interview

6

Offer

Common questions

Technical Knowledge

Behavioral/STAR

Past Experience

Data Analysis/Statistics

Culture Fit