We are seeking a Sr. Technical Program Manager (TPM) to lead complex, cross-functional initiatives that drive delivery of high-impact features and products. This role sits at the intersection of product, engineering, data science, and operations—ensuring alignment, execution, and measurable outcomes across multiple teams. The TPM will own end-to-end program execution, from planning through delivery, while proactively managing risks, dependencies, and stakeholder expectations.
The ideal candidate will have demonstrated an ability to execute, be comfortable operating in ambiguous environments and is able to navigate across stakeholders while maintaining focus on delivering customer value. You should have a track record of successfully launching sophisticated technical products or features and have experience with ML/AI implementations (in healthcare preferred). The unique opportunity to shape a product from inception, backed by Amazon's resources and reach, makes this an exceptional role for a TPM passionate about improving healthcare outcomes through technology innovation.

• Key job responsibilities
• Work closely with product and technical development teams to define program scope, goals, milestones and success metrics
• Drive execution of cross-functional programs spanning product, engineering, and data science teams
• Collaborate closely with data science and engineering teams to understand system architecture, technical constraints and coordinate necessary trade-offs to maximize value to customers
• Track and communicate progress, identify risks and proactively mitigate issues/blockers
• Establish and lead program management best practices, tools, and team ceremonies (including stand-ups, sprint planning, sprint demos)
• Drive continuous improvement through retrospectives and performance metrics

A day in the life
You check in with technical leads, scientists, product managers, and engineers to align on progress and priorities. When unexpected results surface, you dig in — pulling data, identifying root causes, and huddling with engineers to formulate and test hypotheses. Findings become new requirements in product specs and roadmap items for the next sprint, with downstream teams informed of impact. You define metrics and establish mechanisms to drive them. You advocate for improvements to systems and processes that benefit your teams and partners. You close the day by writing a document for leadership capturing progress, decisions, risks, and mitigation plans.

About the team
Innovators wanted! Are you an entrepreneur? A builder? A dreamer? This role is part of an Amazon Special Projects team that amplifies the company’s Think Big leadership principle. We focus on creating entirely new products and services with a goal of positively impacting the lives of our customers. No industries or subject areas are out of bounds. If you’re interested in innovating at scale to address big challenges in the world, this is the team for you.

Here at Amazon, we embrace our differences. We are committed to furthering our culture of inclusion. We have thirteen employee-led affinity groups, reaching 40,000 employees in over 190 chapters globally. We are constantly learning through programs that are local, regional, and global. Amazon’s culture of inclusion is reinforced within our 16 Leadership Principles, which remind team members to seek diverse perspectives, learn and be curious, and earn trust.

Our team highly values work-life balance, mentorship and career growth. We believe striking the right balance between your personal and professional life is critical to life-long happiness and fulfillment. We care about your career growth and strive to assign projects and offer training that will challenge you to become your best.

Basic Qualifications

• Bachelor's degree in engineering, statistics, computer science, mathematics, or a related quantitative field
• 5+ years of technical product or program management experience
• Experience working with technical and product stakeholders to define requirements, prioritize features, and influence product roadmaps
• • Strong understanding of software development life cycle (SDLC) and agile methodologies
• • Demonstrated experience launching complex technical features and/or products
• • Experience contributing to engineering discussions around technology, feature delivery and tradeoff decisions
• • Track record of working with ML/AI technologies in regulated industries
• • Excellent communication and stakeholder management skills

Preferred Qualifications

• Experience defining KPI's/SLA's used to drive multi-million dollar businesses and reporting to senior leadership
• Experience working with, presenting to and influencing senior executives up to VP level
• • Advanced degree (MS/PhD) in engineering, Computer Science, Life Sciences, Physical Sciences, or related quantitative field
• • Strong understanding of healthcare regulations and industry compliance requirements
• • Previous experience with healthcare APIs and system integrations

Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.

Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit https://amazon.jobs/content/en/how-we-hire/accommodations for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.

The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits.

USA, WA, Seattle - 148,700.00 - 201,200.00 USD annually