We are currently seeking a highly motivated and passionate scientist to join our team in Immunology Discovery based in Cambridge MA. This lab-based individual will be responsible for cellular/molecular functional assays to support novel target identification/validation and early portfolio programs within GI immunology. The scientist is expected to read and adapt scientific literature and internal protocols to accomplish assignments and demonstrate broad and versatile technical expertise within immunology. The position requires ability to work independently, deliver reliable results in a timely manner, have excellent technical, written and oral communication skills and work very well in a collaborative team environment.

Key responsibilities

• Independently develop, execute and analyze functional assays using human cell lines and primary cells for screening molecules and testing hypothesis.
• Perform advanced molecular and cellular biology techniques (including but not limited to FACS, ELISA, MSD, HTRF) to measure cellular activation, differentiation and effector molecule production.
• Isolate, culture or differentiate immune cells (PBMCs, T cells, myeloid cells) from human and mouse blood products or tissues.
• Require minimum supervision for established protocols and routine methods.
• Implement and innovate new experimental protocols/techniques as needed.
• Analyze, interpret, document and report data consistently, concisely and rigorously, both to individual stakeholders and in group settings.
• Demonstrate scientific excellence through dedication to multiple projects with different priority requirements in a fast-paced multi-disciplinary environment,
• Impact projects mostly through lab-based activities
• Bachelor’s Degree with typically 5 years of relevant industry experience, OR Master’s Degree with typically 2 years of relevant industry experience.
• Robust experience with in-vitro cell culture (sterile techniques, handling challenging cell types) and cell-based assays development is required.
• Robust experience with human PBMC functional assays and/or immune cells culture/co-culture assays (T cells and myeloid cells) is required.
• Robust experience in immunoassays including multi-color flow cytometry and ELISA (or MSD, HTRF) is required.
• Experience with mouse tissue processing for immune profiling (not direct mouse handling) is a plus.
• Knowledge of DNA/RNA handling and other molecular biology techniques like PCR, qPCR and Western blotting is a plus.
• Ability to learn new skills and apply them in a fast-paced research environment.
• Creativity, problem-solving, and attention to details.
• Excellent oral and written communication and collaboration skills.
• Ability to work independently as well as in a team.
• Proven flexibility to deal with changing timelines and shifting work priorities.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

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About Abb Vie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.