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Sr Manager, Systems Design Engineering

Thermo Fisher

Sr Manager, Systems Design Engineering

Thermo Fisher

Singapore, Singapore

·

On-site

·

Full-time

·

2w ago

Required Skills

Systems engineering

Product development

Team leadership

Technical communication

Project management

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description Senior Manager, Systems Engineering – qPCR Platforms

About the Role

In the role of Systems Engineering Senior Lead, you’ll be the architect and technical owner of our next-generation qPCR systems. You’ll bring together hardware, software, assays, algorithms, and consumables into one cohesive platform — driving innovation from concept to commercialization!

This role blends strategic leadership with hands-on technical depth. You’ll lead a team of architects and engineers, partner with business and product leaders, and ensure every system we build is reliable, scalable, and ground-breaking for our customers.

What You’ll Do Own the System Architecture

  • Define and own the system architecture for integrated qPCR platforms spanning hardware, software, assay, and algorithm development.

  • Translate user needs and business goals into clear system requirements that balance performance, usability, manufacturability, and compliance.

  • Lead design trade-offs and technical risk analyses to ensure robustness and scalability.

  • Champion the architectural vision from early concept through final commercial product.

Lead multi-functional Integration

  • Partner closely with Product Management, Operations, Assay,Software, and Algorithm teams to align technology and product strategies.

  • Drive system-level integration, ensuring seamless collaboration across fields and geographies.

  • Communicate complex technical decisions and trade-offs to senior collaborators with clarity and influence.

  • Work hand-in-hand with Manufacturing, Quality, and Service teams to ensure design choices enable smooth scale-up and long-term reliability.

Drive Innovation and Execution

  • Serve as the hands-on technical authority for system definition, integration, and root-cause analysis.

  • Guide technology down-selection, system verification, and early-stage prototyping efforts.

  • Advance systems engineering practices — adopting model-based methods, simulation tools, and data-driven approaches.

  • Champion new technologies and ideas that push the boundaries of what’s possible in qPCR instrumentation.

Build and Develop the Team

  • Recruit, mentor, and empower an extraordinary systems engineering team.

  • Create a culture that values innovation, rigor, and collaborative problem-solving.

  • Provide mentorship and growth opportunities for emerging technical leaders.

  • Shape and scale systems engineering excellence across the broader R&D organization.

What You Bring

  • 8 years of experience in systems engineering or multi-functional product development for life science or diagnostic instruments.

  • Proven record of leading system integration across hardware, software, and consumables — from concept to launch.

  • Demonstrated success managing and developing successful technical teams.

  • Strong experience working in regulated environments (ISO 13485, FDA QSR, CE-IVD).

  • Ability to partner strategically with Product Management and business leaders to translate vision into executable roadmaps.

  • Deep understanding of systems engineering principles and broad technical fluency across mechanical, electrical, software, and assay domains.

  • Excellent communication and influencing skills; comfortable communicating complex ideas to both engineers and executives.

Education

  • Bachelor’s, Master’s, or Ph.D. in Engineering (Mechanical, Electrical, Systems, or Software) or Applied Physics; advanced degree preferred.

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About Thermo Fisher

Thermo Fisher

Thermo Fisher Scientific Inc. is an American life science and clinical research company. It is a global supplier of analytical instruments, clinical development solutions, specialty diagnostics, laboratory, pharmaceutical and biotechnology services.

10,001+

Employees

Waltham

Headquarters

Reviews

3.9

2 reviews

Work Life Balance

3.5

Compensation

2.5

Culture

3.5

Career

4.0

Management

3.0

65%

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Pros

Large company with extensive resources

Structured internship program

Career opportunities in product management

Cons

Low compensation ($22/hour)

High cost of living in location

Expensive housing/rent

Salary Ranges

2,260 data points

Mid/L4

Mid/L4 · Advanced Product Design Specialist

3 reports

$164,375

total / year

Base

$126,443

Stock

-

Bonus

-

$148,260

$164,375

Interview Experience

8 interviews

Difficulty

3.0

/ 5

Duration

14-28 weeks

Offer Rate

12%

Experience

Positive 12%

Neutral 63%

Negative 25%

Interview Process

1

Application Review

2

Recruiter Screen

3

Hiring Manager Interview

4

Panel Interview

5

Final Interview

6

Offer

Common Questions

Technical Knowledge

Behavioral/STAR

Past Experience

Culture Fit

Industry Specific