Jobs
Natera is a global leader in cell-free DNA (cfDNA) testing with a focus on women's health, oncology, and organ health. To bolster our oncology products, we are looking for a Senior Bioinformatics Engineer to provide technical expertise and process completion. Through collaboration between the product and development teams, the Senior Bioinformatics Engineer will help complete projects for the array of Oncology bioinformatics pipelines.
Responsibilities
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Develop, maintain, and scale production-grade bioinformatics pipelines
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Lead the translation of validated research workflows into scalable, automated, cloud-based production systems
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Architect and drive automation initiatives to improve pipeline scalability, reliability, reproducibility, and turnaround time (TAT)
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Design and oversee secure, high-throughput data transfer solutions across AWS accounts
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Proactively identify bottlenecks and implement performance and cost optimizations
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Contribute to long-term roadmap planning for automation and production pipeline evolution
Minimum Qualifications
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Master’s degree in Bioinformatics, Computational Biology, Computer Science, or related quantitative field
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5+ years of experience developing and operating bioinformatics or large-scale data processing pipelines in production environments
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Strong proficiency in a production programming language (e.g., Python)
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Extensive experience working in AWS or comparable cloud platforms
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Proven ability to design scalable, automated systems with minimal manual intervention
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Demonstrated experience owning automated pipelines end-to-end, including debugging across data, application, and infrastructure layers
Knowledge, Skills, and Abilities
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Deep expertise with workflow orchestration tools (e.g., WDL, Nextflow, Snakemake)
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Strong experience with Docker and containerized execution at scale
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Advanced knowledge of AWS services such as S3, EC2, AWS Batch, Airflow, and IAM, including multi-account architectures
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Experience leading automation efforts and driving technical improvements across teams
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Experience handling large genomic datasets
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Strong understanding of software engineering best practices, including CI/CD, unit testing, and test-driven development
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Excellent communication skills and ability to influence technical direction across scientific and engineering stakeholders
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Team player, self-motivated and detail oriented are essential
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page
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About Natera

Natera
PublicSpecializes in non-invasive, cell-free DNA (cfDNA) testing technology, with a focus on women’s health, cancer, and organ health.
1,001-5,000
Employees
Austin
Headquarters
Reviews
4.2
27 reviews
Work Life Balance
3.5
Compensation
4.6
Culture
4.4
Career
4.2
Management
3.9
78%
Recommend to a Friend
Pros
Cutting-edge technology stack and interesting technical challenges
Competitive compensation packages with equity
Strong engineering culture with focus on code quality
Cons
Fast-paced environment with tight deadlines
Work-life balance can be challenging during product launches
Organizational changes and restructuring can be disruptive
Salary Ranges
79 data points
Mid/L4
Senior/L5
Director
Mid/L4 · BIOSTATISTICIAN
1 reports
$129,143
total / year
Base
$99,341
Stock
-
Bonus
-
$129,143
$129,143
Interview Experience
46 interviews
Difficulty
3.4
/ 5
Duration
14-28 weeks
Offer Rate
30%
Experience
Positive 60%
Neutral 24%
Negative 16%
Interview Process
1
Phone Screen
2
Technical Interview
3
System Design
4
Behavioral
5
Team Fit
Common Questions
Tell me about a challenging project
System design question
Coding problem
Why this company
News & Buzz
Short Interest in Natera, Inc. (NASDAQ:NTRA) Declines By 27.2% - MarketBeat
Source: MarketBeat
News
·
4w ago
Natera, Inc. $NTRA Shares Purchased by Mirae Asset Global Investments Co. Ltd. - MarketBeat
Source: MarketBeat
News
·
4w ago
Natera, Inc. (NTRA) Reports Preliminary Q4 Revenue - Insider Monkey
Source: Insider Monkey
News
·
5w ago
Natera, Inc. (NTRA) Reports Preliminary Q4 Revenue - Finviz
Source: Finviz
News
·
5w ago