Site: The General Hospital Corporation

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

This Clinical Research Coordinator I role is embedded in Dr. Vamsi Mootha’s laboratory—with Dr. Mootha serving as the lead PI of the Mitochondrial Medicine Unit—and operates under the clinical direction of Dr. Walker (Neurology) and Dr. Sharma (Medicine) to advance translational research in mitochondrial disease. The position integrates human‑subject activities with bench‑based methods (e.g., clinical procedures and core molecular techniques).

In addition to the baseline CRC I responsibilities, the position requires laboratory competencies central to mitochondrial research, including human biospecimen processing and handling, basic cell culture, and molecular assays such as qPCR and ELISA, enabling direct linkage between clinical phenotypes and bench‑based analyses.

The role also entails management of a disease‑specific research registry and biorepository—with responsibilities for aliquoting, coding, long‑term storage, and compliant shipping—to ensure high‑quality, retrievable samples for current and future studies.

Programmatic and collaborative expectations include presenting progress in weekly meetings, assisting with conferences such as the Mito Case seminar series, and providing administrative support for educational initiatives of the MGH Mitochondrial Medicine Unit, thereby extending impact beyond individual studies.

The coordinator will partner with national patient‑advocacy organizations (e.g., UMDF, Mito‑Action, FARA) and coordinate across multiple institutions, activities that are essential to advancing research in rare mitochondrial disorders.

Finally, the position provides regulatory support at a level commensurate with complex rare‑disease research, including QA/QC, proof‑reading of regulatory and scholarly documents, and assistance with submissions up to and including Expanded Access/Compassionate Use IND protocols.

Given the highly specialized nature of the work, it is imperative that candidates possess direct and demonstrable experience across all of the above domains—including mitochondrial or related molecular biology techniques, biospecimen handling, biorepository operations, and rare‑disease research coordination—in order to successfully fulfill the responsibilities of this role.

Additionally, preferred qualifications include a bachelor’s degree with 3–12 months of prior mitochondrial molecular biology or similar bench research experience, as well as prior record‑keeping, archival, or patient‑interaction experience, which are necessary to perform the unique research, regulatory, and collaborative functions required.

Job Summary:

Job Profile Summary:

Summary:

Following established policies, procedures, and study protocols, provides assistance on clinical research studies, including recruiting, evaluating, and consenting patients for studies; collecting and organizing patient data; scheduling patients for study visits; performing clinical tests such as phlebotomy, EKGs, etc.; and maintaining and updating data generated by the study. Candidates who are in the process of completing their bachelor's degree have a six-month grace period from their hire date (up to one year if starting on a per diem basis) to provide degree equivalency verification.

Does this position require Patient Care?
No

Essential Functions
-Reviews proposals for compliance with sponsor and organizational guidelines; verifies that all sponsor requirements are met.

-Recruiting patients for clinical trials and conducting phone interviews.

-Verifies the accuracy of study forms and updates them per protocol.

-Prepares data for analysis and data entry.

-Documents patient visits and procedures.

-Assists with regulatory binders and QA/QC Procedures.

-Assists with interviewing study subjects.

-Assists with study regulator submissions.

Qualifications:

Job Profile Summary Summary:

Following established policies, procedures, and study protocols, provides assistance on clinical research studies, including recruiting, evaluating, and consenting patients for studies; collecting and organizing patient data; scheduling patients for study visits; performing clinical tests such as phlebotomy, EKGs, etc.; and maintaining and updating data generated by the study. Candidates who are in the process of completing their bachelor's degree have a six-month grace period from their hire date (up to one year if starting on a per diem basis) to provide degree equivalency verification.

Does this position require Patient Care?
No

Essential Functions
-Reviews proposals for compliance with sponsor and organizational guidelines; verifies that all sponsor requirements are met.

-Recruiting patients for clinical trials and conducting phone interviews.

-Verifies the accuracy of study forms and updates them per protocol.

-Prepares data for analysis and data entry.

-Documents patient visits and procedures.

-Assists with regulatory binders and QA/QC Procedures.

-Assists with interviewing study subjects.

-Assists with study regulator submissions.

Additional Job Details (if applicable)

Remote Type

Onsite

Work Location

185 Cambridge Street

Scheduled Weekly Hours:

40

Employee Type

Regular

Work Shift

Day (United States of America)

Pay Range

$20.16 - $29.01/Hourly

Grade

5

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement:

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.