Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

GRAIL is seeking a Senior IT Network Engineer to join our IT Infrastructure team. In this role, you will be a hands-on technical contributor responsible for building, operating, and supporting secure, scalable, and highly available network infrastructure across AWS and hybrid environments. You will play a critical role in enabling reliable connectivity for GRAIL’s cloud platforms, on-premise systems, and mission-critical applications that support early cancer detection.

This role emphasizes deep technical execution and operational ownership. You will design, implement, monitor, and troubleshoot AWS networking—primarily Amazon VPC–based architectures—while also supporting on-premise and data center networking using Juniper and Aruba platforms and Palo Alto firewalls. You will partner closely with Platform, Security, SRE, and Application teams to ensure performance, availability, and security across the network stack.

This is a hybrid role based in Durham, NC. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site.