At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Lilly, a leading innovation-driven corporation is developing a growing portfolio of pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in Indianapolis, Indiana, Lilly makes life better – through medicines and information – for some of the world’s most urgent medical needs. Founded 150 years ago, the company has sustained a culture that values excellence, integrity and respect for people. This has resulted in Lilly frequently being ranked as one of the best companies in the world at which to work. Lilly knows its business has prospered because of its employees – people with a talent for innovation and a passion for making a difference by finding treatments for the most stubborn diseases; people whose talent is matched by their generosity, and people with strong values and a determination to prevail, regardless of the challenges. Join our team – and make a difference in improving health for people all over the world!

Position Overview:

Reporting into the Process Development team of Lilly’s Gene Therapy Discovery and Platform Research (GTDPR) group, the Advisor will play a critical role in our efforts to support program advancement and lead research projects of upstream manufacturing for Lilly’s gene therapy pipeline.

We are looking for an enthusiastic, self-motivated, hands-on candidate with excellent interpersonal skills who is comfortable working in an open environment spanning multiple functions.

Key Responsibilities:

• Lead projects that support AAV program advancement from candidate selection to FTD
• Lead projects that improve current AAV platform processes
• Design and implement experiments to optimize upstream processes in transient or stable systems
• Support the production and characterization of engineered AAV capsids, including variant screening, titer optimization, product quality, and expression profile.
• Operate and optimize suspension cell culture in shake flasks and small-scale bioreactors (e.g., AMBR250, Bio Stat, BioBLU, Hy Performa)
• Collaborate cross-functionally with vector design, purification, analytical, nonclinical, and/or manufacturing teams to own and monitor end-to-end process performance.
• Assist in lab capability building to improve throughput or efficiency
• Effectively coach scientists to develop their critical thinking and technical skills
• Author technical reports, development protocols, and regulatory-supporting documentation.

Basic Requirements:

• PhD with 2+ years, MS with 7+ years, or BS with 12+ years of relevant industry experience with a degree in a scientific field (cell biology, molecular biology, biochemistry, chemical engineering).

Additional Skills/Preferences

• Experience in AAV production and AAV biology
• Experience working in CMC and cGMP
• Knowledge in cell biology, molecular biology, scale-up and tech transfer
• Excellent verbal and written communications skills.
• Strong analytical and problem-solving skills.
• Creative thinking, high level of ownership, multitasking in a fast-paced work environment.
• Strong organizational and problem-solving skills and attention to detail.

Additional Information:

• Location: Seaport District, Boston, Massachusetts
• Position requires on-site presence, 8-hour days, five days per week
• 0-10% travel

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$138,000 - $224,400

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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