Are you passionate about leveraging AI to revolutionize life sciences? AWS Life Sciences Applied AI is seeking a visionary Principal Product Manager to lead the development of applications that reimagine how clinical trials are designed, executed, and delivered. As part of the AWS Applied AI organization, we have a vision to provide business applications, leveraging Amazon's unique experience and expertise, that are used by millions of companies worldwide to manage day-to-day operations. We will accomplish this by accelerating our customers' businesses through delivery of intuitive and differentiated technology solutions that solve enduring business challenges. We blend vision with curiosity and Amazon's real-world experience to build opinionated, turnkey solutions. Where customers prefer to buy over build, we become their trusted partner with solutions that are no-brainers to buy and easy to use.
Key job responsibilities
As Principal Product Manager, you'll lead pioneering product development for AI-driven clinical trials transformation. You'll guide a team of builders (product managers, developers, and scientists) to invent and simplify on behalf of pharmaceutical companies, biotech firms, and clinical operations teams—defining novel, generative AI agent-based experiences that help them accelerate the path from discovery to treatment. You will drive innovation by reimagining how clinical evidence is generated and how trial operations are managed, replacing fragmented manual processes with intelligent, continuously learning systems. This is a highly visible and impactful role within AWS, offering the opportunity to shape the future of clinical development and drive innovation at a global scale. You will be responsible for defining key product directions, adopting or inventing new machine learning techniques, reimagining user workflows and experiences, and fundamentally changing how life-saving therapies reach patients.
About the team
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Basic Qualifications

• 7+ years of working as a Technical Product Manager experience
• 5+ years of technical (software development, network development, IT, other related) experience
• Experience delivering large-scale SaaS, PaaS or LaaS products where you are responsible for the full product lifecycle, from concept through GTM (go to market)
• Experience with clinical development workflows, including evidence generation, data transformation, or clinical operations
• Demonstrated understanding of clinical trial processes, regulatory submissions, and clinical data standards (e.g., CDISC, SDTM, ADaM)

Preferred Qualifications

• Advanced degree (MS or PhD) in Biostatistics, Clinical Informatics, Health Informatics, or related field, or equivalent industry experience
• Track record of successful product launches that leverage ML/AI technologies
• Strong technical background with ability to evaluate emerging technologies and contribute to technical discussions around clinical data systems and agentic AI
• Experience leading cross-functional teams and collaborating with research scientists, engineers, and business stakeholders
• Proven ability to translate complex clinical and regulatory concepts into clear product requirements and user experiences
  Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.
  Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit https://amazon.jobs/content/en/how-we-hire/accommodations for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.

The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits.

USA, WA, Seattle - 181,100.00 - 245,000.00 USD annually