Who We Are

We are a group of individuals passionate about genetic discovery. 23and Me Research Institute is a nonprofit medical research organization that enables people everywhere to access their genetic information, learn about themselves, and participate in the world's largest crowdsourced research initiative. The Institute aims to be the world's most significant contributor to scientific advancement, uniting people with the common goal of improving health and deepening our understanding of DNA — the code of life.

The Opportunity

We’re seeking a Senior Director of Performance and Growth Marketing who is part scientist, part strategist, and part scrappy growth hacker. You live and breathe experimentation, velocity, and measurable impact. You know how to build momentum with tiny budgets, test your way to insights, and harness data, AI, and emerging channels to reach new audiences efficiently.

This isn’t a “big brand, big budget” job — it’s a build, test, learn, and scale role. You will architect a modern, agile growth system built on rapid experimentation, constantly seeking to improve our LTV/CAC ratio. This system will derive leverage by integrating precision acquisition (geo-targeted activations and advanced performance media techniques), high-leverage partnerships (measurable influencer collaborations), advanced data strategy (synthetic audience generation and predictive modeling), creative velocity (machine learning-powered creative optimization).

You will lead a high-velocity growth organization, managing the Director of Growth Marketing and the Director of Acquisition, Retail, and International Marketing. You will empower this team and external agency partners to build, optimize, and scale a global, data-driven performance engine.

Given 23and Me's direct-to-consumer (DTC) model, your mandate is to architect and govern the end-to-end full-funnel strategy, moving beyond channel execution. You will establish the data requirements and collaborative frameworks with Product and Engineering necessary to optimize the entire conversion pathway—from landing page experiences to checkout flows and post-purchase activation. Your success is defined by establishing the LTV/CAC optimization model and ensuring the Directors' strategies accelerate customer activation and drive long-term profitability. Your ability to succeed hinges on establishing high-tempo operational alignment with Product, Engineering, Brand, and Data Science to define, instrument, and improve the core conversion architecture.

What You’ll Do

• Architect the global growth engine — define the structure, measurement, and optimization framework and governance for a cohesive, multi-channel performance marketing system, including establishing standards for budget allocation, attribution modeling, and inter-channel dependency to drive efficient new customer acquisition and scale across key platforms (including paid search, paid social, programmatic display, affiliate, influencer, email, SMS, and new/emerging channels).
• Run high-velocity experimentation — design, implement, and govern the acquisition and conversion framework for high-velocity experimentation, ensuring rigor in A/B and multivariate testing across messaging, creative, and audience segments.
• Lead the implementation of Generative AI and Automation across the funnel—from synthetic audience creation and predictive targeting to dynamic creative optimization and Answer Engine Optimization (AEO)/Generative Engine Optimization (GEO) for emerging search platforms.
• Drive full-funnel performance — from efficient acquisition to activation and conversion. Establish a robust incrementality framework to measure true campaign value including intelligent attribution, driving a shift from a ROAS mindset to an LTV/CAC optimization model.
• Turn data into direction — create tight feedback loops between analytics, creative, and channel execution.
• Drive Cross-Functional Strategy— Collaborate closely with Director/VP/C-level stakeholders across Brand, Product, Engineering, and Data Science to ensure growth insights are translated directly into business strategy, product roadmaps, and long-term brand positioning.
• Be resourceful and inventive — make every dollar work harder through creative partnerships, earned amplification, and channel innovation.
• Build a culture of learning and trust — mentor your team to think in terms of hypotheses, experiments, and outcomes rather than campaigns and channels. Scale growth efficiently while maintaining customer trust, regulatory compliance, and data privacy.
• Roll up your sleeves — drive execution and help out. We operate with a lean, ownership-driven mindset, where every leader is expected to be an executive player-coach.

What You’ll Bring

• 10–12+ years of highly relevant experience, with at least 3-5 years operating as a hands-on executive who successfully architected and efficiently scaled a multi-channel performance engine in a high-growth, resource-constrained D2C or tech environment, while simultaneously managing Director-level reports and driving strategic initiatives in partnership with Product/Eng/Brand teams.
• Proven success scaling efficiently — you’ve grown measurable outcomes without massive budgets.
• Deep knowledge of paid search, paid social, display, programmatic, affiliate, and influencer ecosystems, with curiosity about what’s next.
• Strong analytics and data literacy — fluent in CAC, LTV, ROAS, incrementality, and attribution models, with the ability to translate data into strategy.
• Demonstrated success leveraging advanced AI/ML capabilities(predictive modeling, audience synthesis, dynamic creative optimization) to drive performance, and familiarity with the strategic implications of Generative AI in customer acquisition.
• A test-and-learn mindset — you move fast, build frameworks for experimentation, and know when to scale or kill a test.
• Excellent collaborator — you can rally creative, product, and executive teams around data-backed insights.
• Passion for 23and Me’s mission — you believe in empowering people with access to their health and genetic information.

Preferred Experience

• Experience with performance marketing platforms and tools
• Familiarity with analytics and experimentation platforms
• Hands-on experience with AI-powered marketing tools for creative generation, predictive targeting, and synthetic audiences
• Experience with geo-targeted campaigns, local activation, or hyper-personalized messaging
• Comfort managing multi-million-dollar budgets, prioritizing channels with maximum ROI, and reporting performance at the executive level
• Experience leading small, high-velocity growth teams, balancing hands-on execution with strategic planning

About Us

23and Me, headquartered in California, is a leading consumer genetics and research company. The company’s mission is to help people access, understand, and benefit from the human genome. 23and Me has pioneered direct access to genetic information as the only company with multiple FDA authorizations for genetic health risk reports. The company has created the world’s largest crowdsourced platform for genetic research, with 80 percent of its customers electing to participate. 23and Me research participants consent to research conducted by 23and Me which is overseen by an independent third-party Institutional Review Board (IRB) regulated under the 'Common Rule' (45 CFR part 46). More information is available at www.23andme.com/research.

At 23and Me, we value a diverse, inclusive workforce and we provide equal employment opportunity for all applicants and employees. All qualified applicants for employment will be considered without regard to an individual’s race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application because of incompatible assistive technology or a disability, please contact us at accommodations-ext@23andme.com. 23and Me will reasonably accommodate qualified individuals with disabilities to the extent required by applicable law.

Please note: 23and Me does not accept agency resumes and we are not responsible for any fees related to unsolicited resumes. Thank you.

Pay Transparency

23and Me takes a market-based approach to pay, and amounts will vary depending on your geographic location. The salary range reflected here is for a candidate based in the San Francisco Bay Area. The successful candidate’s starting pay will be determined based on job-related skills, experience, qualifications, work location, and market conditions. These ranges may be modified in the future.

San Francisco Bay Area Base Pay Range**$275,000—$350,000 USD**